1-(2-氟苯基)环已烷羧酸合成路线 (共 11 条)
反应条件
chromium(VI) oxide; aluminium trichloride; sulfuric acid 1.) methylene dichloride, 5 deg C, 3 min; 2.) acetone, 20 deg C, 4 h; Yield given. Multistep reaction;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 349 - 360
反应条件
1: MCPBA 2: AlCl3 / CH2Cl2 3: CrO3 View Scheme
参考文献
Tetrahedron Letters, , vol. 23, # 19 p. 2053 - 2056
反应条件
2: MCPBA 3: TFA / CH2Cl2 / 15 h / 20 °C 4: CrO3 View Scheme
参考文献
Tetrahedron Letters, , vol. 23, # 19 p. 2053 - 2056
反应条件
2: MCPBA 3: AlCl3 / CH2Cl2 4: CrO3 View Scheme
参考文献
Tetrahedron Letters, , vol. 23, # 19 p. 2053 - 2056
反应条件
1: MCPBA 2: TFA / CH2Cl2 / 15 h / 20 °C 3: CrO3 View Scheme
参考文献
Tetrahedron Letters, , vol. 23, # 19 p. 2053 - 2056
反应条件
1: TFA / CH2Cl2 / 15 h / 20 °C 2: CrO3 View Scheme
参考文献
Tetrahedron Letters, , vol. 23, # 19 p. 2053 - 2056
反应条件
1: 88 percent / toluene / 16 h / Heating 2: 66 percent / sodium ethoxide / ethanol / 0.5 h / Heating 3: 89 percent / m-chloroperbenzoic acid / CHCl3 / 3.5 h / 0 °C 4: 1.) aluminium trichloride; 2.) chromium trioxide, 98percent sulphuric acid / 1.) methylene dichloride, 5 deg C, 3 min; 2.) acetone, 20 deg C, 4 h View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 349 - 360
反应条件
1: 66 percent / sodium ethoxide / ethanol / 0.5 h / Heating 2: 89 percent / m-chloroperbenzoic acid / CHCl3 / 3.5 h / 0 °C 3: 1.) aluminium trichloride; 2.) chromium trioxide, 98percent sulphuric acid / 1.) methylene dichloride, 5 deg C, 3 min; 2.) acetone, 20 deg C, 4 h View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 349 - 360
参考文献
Tetrahedron Letters, , vol. 23, # 19 p. 2053 - 2056
反应条件
jones reagent; ozone 1.) 0 deg C, 3 h; 2.) 0 deg C.; Yield given. Multistep reaction;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 349 - 360