3-甲氧基-2-氨基苯甲酰胺合成路线 （共 9 条）
反应条件
1: With 1,1'-carbonyldiimidazole in N,N-dimethyl-formamide T=70°C; 1 h; Inert atmosphere; 2: With ammonium hydroxide in N,N-dimethyl-formamide
参考文献
Nathubhai, Amit; Patterson, Richard; Woodman, Timothy J.; Sharp, Harriet E. C.; Chui, Miranda T. Y.; Chung, Hugo H. K.; Lau, Stephanie W. S.; Zheng, Jun; Lloyd, Matthew D.; Thompson, Andrew S.; Threadgill, Michael D.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 17 p. 6089 - 6099
反应条件
nickel monoaluminide in ethanol
反应条件
ammonium hydroxide in dichloromethane 1 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 6 p. 1844 - 1848
反应条件
pyridine in tetrahydrofuran T=25°C;
参考文献
Griffin, Roger J.; Srinivasan, Sheila; Bowman, Karen
Journal of Medicinal Chemistry, 1998 , vol. 41, # 26 p. 5247 - 5256
反应条件
potassium carbonate in water; acetonitrile
参考文献
Newcastle University Ventures Limited
Patent: US6156739 A1, 2000 ;
反应条件
1: 31 percent / pyridine / tetrahydrofuran / 25 °C 2: 67 percent / aq. NaOH / Ambient temperature View Scheme
参考文献
Griffin; Srinivasan; White; Bowman; Calvert; Curtin; Newell; Golding
Pharmaceutical Sciences, 1996 , vol. 2, # 1 p. 43 - 47
反应条件
1: 31 percent / pyridine / tetrahydrofuran / 25 °C 2: 67 percent / aq. NaOH / Ambient temperature 3: 65 percent / BBr3 / CH2Cl2 / Heating View Scheme
参考文献
Griffin; Srinivasan; White; Bowman; Calvert; Curtin; Newell; Golding
Pharmaceutical Sciences, 1996 , vol. 2, # 1 p. 43 - 47
反应条件
in N,N-dimethyl-formamide T=150°C; 24 h;
参考文献
Nathubhai, Amit; Patterson, Richard; Woodman, Timothy J.; Sharp, Harriet E. C.; Chui, Miranda T. Y.; Chung, Hugo H. K.; Lau, Stephanie W. S.; Zheng, Jun; Lloyd, Matthew D.; Thompson, Andrew S.; Threadgill, Michael D.
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 17 p. 6089 - 6099
反应条件
1: 87 percent / pyridine / tetrahydrofuran / 25 °C 2: 66 percent / aq. NaOH / 2 h / 100 °C 3: 38 percent / BBr3 / CH2Cl2 / Heating View Scheme
参考文献
Griffin; Srinivasan; White; Bowman; Calvert; Curtin; Newell; Golding
Pharmaceutical Sciences, 1996 , vol. 2, # 1 p. 43 - 47
