3,4-二氢-3-氧代-2H-(1,4)-苯并噁嗪-2-基-乙酸合成路线 （共 8 条）
反应条件
1: With triethylamine in 1,4-dioxane T=20°C; 12 h; Reflux; 2: With hydrogenchloride in water
参考文献
WO2012/127385 A1, ;
Page/Page column 56 ;
反应条件
triethylamine in 1,4-dioxane T=20°C; 12 h; Reflux;
参考文献
WO2013/136288 A1, ;
Page/Page column 29; 30 ;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 1 p. 159 - 162
反应条件
1: toluene / 3 h / 20 °C 2: triethylamine / 1,4-dioxane / 12 h / 20 °C / Reflux View Scheme
反应条件
potassium hydroxide in water 0.333333 h; Heating;
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 42, # 4 p. 905 - 909
反应条件
1: K2CO3 / ethanol / 3 h / 20 °C 2: 2N KOH / H2O / 0.33 h / Heating View Scheme
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 42, # 4 p. 905 - 909
反应条件
1: trimethylaluminum / toluene / 5.25 h / 50 - 110 °C / |Inert atmosphere 2: triethylamine / 1,4-dioxane / 12 h / 20 °C / |Reflux View Scheme
反应条件
triethylamine 3 h; Heating;
参考文献
Australian Journal of Chemistry, , vol. 39, # 3 p. 503 - 510
