5,6-亚甲基二氧吲哚-3-羧酸合成路线 （共 6 条）
反应条件
lithium hydroxide; water in 1,4-dioxane T=25°C; 15 h;
参考文献
The Scripps Research Institute
Patent: US2005/26987 A1, 2005 ;
Location in patent: Page 30 ;
反应条件
lithium hydroxide hydrate in ethanol 16 h; Reflux;
参考文献
NOVARTIS AG; JIRICEK, Jan; KONDREDDI, Ravinder Reddy; SMITH, Paul William
Patent: WO2014/37900 A1, 2014 ;
Location in patent: Page/Page column 32 ;
反应条件
1: sodium methoxide / methanol / 4 h / -15 °C 2: xylene / 0.25 h / Heating 3: KOH / H2O / 1 h / Heating View Scheme
参考文献
Molecules, , vol. 11, # 12 p. 968 - 977
反应条件
1: xylene / 0.25 h / Heating 2: KOH / H2O / 1 h / Heating View Scheme
参考文献
Molecules, , vol. 11, # 12 p. 968 - 977
反应条件
1: anhydrous xylene / 3 h / 150 °C 2: lithium hydroxide hydrate / ethanol / 16 h / |Reflux View Scheme
反应条件
water; boron tribromide in dichloromethane T=-40°C; 4 h;
参考文献
Molecules, , vol. 11, # 12 p. 968 - 977
