1: With pyridine; phosphorus pentachloride in dichloromethane T=20°C; 0.5 h; 2: (7R,8R)-7-phenylacetamido-3-[propen-1-yl]-3-cephem-4-carboxylic acid p-methoxybenzyl ester in dichloromethane 2 h; 3: With Propylene glycol; water; ortho-cresol more than 3 stages;

1: With carbon in water pH=8 - 8.5; 0.25 h; 2: With hydrogenchloride in water T=20°C; pH=3 - 3.5; 0.5 h;

1: (6R,7R)-7-amino-3-[(Z)-1-propen-1-yl]-3-cephem-4-carboxylic acid With 1H-imidazole; chloro-trimethyl-silane in dichloromethane 3 - 4 h; Heating / reflux; 2: C16H19NO7 in DMF (N,N-dimethyl-formamide); dichloromethane T=-45 - -20°C; 2.5 h; 3: With hydrogenchloride in DMF (N,N-dimethyl-formamide); dichloromethane; water T=0 - 5°C; 0.25 h;