(8S,10S)-10-[(3-氨基-2,3,6-三脱氧-alpha-L-吡喃来苏己糖基)氧基]-8-(2-溴-1,1-二甲氧基乙基)-7,8,9,10-四氢-6,8,11-三羟基-1-甲氧基-5,12-并四苯醌合成路线 （共 2 条）
→
106401-68-7(8S,10S)-10-[(3-氨基-2,3,6-三脱氧-alpha-L-吡喃来苏己糖基)氧基]-8-(2-溴-1,1-二甲氧基乙基)-7,8,9,10-四氢-6,8,11-三羟基-1-甲氧基-5,12-并四苯醌
反应条件
bromine in 1,4-dioxane; methanol T=12°C; 2 h;
参考文献
Meyer-Losic, Florence; Quinonero, Jerome; Dubois, Vincent; Alluis, Bertrand; Dechambre, Mireille; Michel, Matthieu; Cailler, Francoise; Fernandez, Anne-Marie; Trouet, Andre; Kearsey, Jonathan
Journal of Medicinal Chemistry, 2006 , vol. 49, # 23 p. 6908 - 6916
→
106401-68-7(8S,10S)-10-[(3-氨基-2,3,6-三脱氧-alpha-L-吡喃来苏己糖基)氧基]-8-(2-溴-1,1-二甲氧基乙基)-7,8,9,10-四氢-6,8,11-三羟基-1-甲氧基-5,12-并四苯醌
反应条件
bromine; orthoformic acid triethyl ester in 1,4-dioxane T=20°C; 1 h;
参考文献
Olsufyeva, Eugenia N.; Tevyashova, Anna N.; Trestchalin, Ivan D.; Preobrazhenskaya, Maria N.; Platt, David; Klyosov, Anatole
Carbohydrate Research, 2003 , vol. 338, # 13 p. 1359 - 1367
