甲基N-{[(2-甲基-2-丙基)氧基]羰基}-D-缬氨酸酯合成路线 （共 5 条）
反应条件
1: 27 percent / diethyl ether / 4 h / 20 °C 2: 26 percent / MeOH; HCl / 20 °C View Scheme
参考文献
Vabeno, Jon; Brisander, Magnus; Lejon, Tore; Luthman, Kristina
Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9186 - 9191
反应条件
hydrogenchloride in 1,4-dioxane 0.5 h; Inert atmosphere;
参考文献
Journal of the American Chemical Society, , vol. 133, # 23 p. 9104 - 9111
反应条件
lithium borohydride in ethanol Yield given;
参考文献
Hamada, Yasumasa; Shibata, Makoto; Sugiura, Tsuneyuki; Kato, Shinji; Shioiri, Takayuki
Journal of Organic Chemistry, 1987 , vol. 52, # 7 p. 1252 - 1255
反应条件
1: 1.) Mg / 1.) THF, reflux, 2.) THF, r.t., 48 h 2: 74 percent / t-BuOK / tetrahydrofuran / 0.5 h / 0 °C View Scheme
参考文献
Bull, Steven D.; Davies, Stephen G.; Jones, Simon; Sanganee, Hitesh J.
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 4 p. 387 - 398
反应条件
1: 1.) Mg / 1.) Et2O, reflux, 2.) Et2O, r.t., 48 h 2: 72 percent / t-BuOK / tetrahydrofuran / 0.5 h / 0 °C View Scheme
参考文献
Bull, Steven D.; Davies, Stephen G.; Jones, Simon; Sanganee, Hitesh J.
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 4 p. 387 - 398
