bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran T=20°C; Negishi Coupling; 0.5 h; Inert atmosphere; Reagent/catalyst; regioselective reaction;

potassium hydroxide; tetrabutylammomium bromide; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran Heating;

1: 3-bromo-pyridine With isopropylmagnesium chloride in tetrahydrofuran T=20°C; 1 h; 2: 2,6-Dibromopyridine With 1,2-bis-(diphenylphosphino)ethane; bis(acetylacetonate)nickel(II) in tetrahydrofuran T=20°C; 18 h;

{PdCl2[(t-Bu)2PCl]2}; cesium fluoride in propan-1-ol T=90°C; Suzuki-Miyaura coupling; 18 h; Inert atmosphere; chemoselective reaction;