1: octadecatrienoic acid With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine in ethyl acetate T=20°C; 1 h; 2: 1-(3,4-dihydroxyphenyl)-2-amino-ethane in ethyl acetate T=20°C; 12 h;

(benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine in tetrahydrofuran 1.) r.t., 10 min, 2.) r.t., 12 h;

triethylamine in N,N-dimethyl-formamide T=4°C; 18 h;

1: Et3N / acetonitrile / 1 h / 4 °C 2: Et3N / dimethylformamide / 18 h / 4 °C View Scheme

4-(N,N-dimethlyamino)pyridine in dichloromethane Acylation;