反应条件
1: 1.) n-butyllithium / 1.) THF/TMEDA 1:1, 2.) RT, 17 h
2: 82 percent / DMAP / triethylamine
3: 79 percent / mCPBA / CH2Cl2 / -78 °C
4: 53 percent / LiOH / H2O; tetrahydrofuran / 50 °C
View Scheme
参考文献
Hiemstra, Henk; Klaver, Wim J.; Speckamp, W. Nico
Tetrahedron Letters, 1986 , vol. 27, # 12 p. 1411 - 1414
