反应条件
1: 4-nitrobenzaldoxime, N,N,N',N'-tetramethylguanidine / dioxane; H2O / 0.05 h / 20 °C
2: pyridine / 1 h / 20 °C
3: 1.) triethylamine, 2-mesitylenesulfonyl chloride, 4-N,N-dimethylaminopyridine, 2.) 1,4-diazabicyclo<2.2.2>octane, triethylamine / 1.) dichloromethane, 20 deg C, 1 h, 2.) dichloromethane, 20 deg C, 1 h
4: acetonitrile / 8 h / 20 °C
5: 1.) triethylamine, 2.) aq. ammonia / 1.) ethanol, 20 deg C, 10 min
View Scheme
参考文献
Zhou, X.-X.; Welch, C.J.; Chattopadhyaya, J.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1986 , vol. 40, # 10 p. 806 - 816
