1,2-双(3-氨丙基氨基)乙烷合成路线 （共 14 条）
反应条件
ammonia; hydrogen; Raney cobalt 2724 T=75 - 80°C; P=20627.1 Torr; 4.5 h; Product distribution / selectivity;
参考文献
US2008/194857 A1, ;
Page/Page column 3-4 ;
反应条件
ammonia; hydrogen; nickel in ethanol
参考文献
J. Med. Chem., , vol. 7, p. 710 - 716
参考文献
Acta Chemica Scandinavica (1947-1973), , vol. 24, p. 247 - 254
反应条件
borane-THF in tetrahydrofuran 7 h; Heating;
参考文献
Synthetic Communications, , vol. 32, # 16 p. 2441 - 2452
反应条件
1: NH3 / methanol / 7 °C 2: BH3*THF / tetrahydrofuran / 7 h / Heating View Scheme
参考文献
Synthetic Communications, , vol. 32, # 16 p. 2441 - 2452
反应条件
1: 91 percent / sodium hydroxide / H2O / 1.) 1 hr., 5 deg C, 2.) r.t., 3 hrs. 2: 85 percent / tetrabutylammonium iodide, sodium hydroxide (50 percent) / toluene; H2O / 9 h / Heating 3: 63 percent / sulfuric acid, (conc.) / 39 h / 100 °C View Scheme
参考文献
Luk'yanenko, N.G.; Basok, S.S.; Filonova, L.K.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, p. 1562 - 1571
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 8 p. 1731 - 1742
反应条件
sodium hydroxide; sodium cyanide; nickel; nickel dichloride Yield given. Multistep reaction;
参考文献
Meunier, I.; Mishra, A. K.; Hanquet, B.; Cocolios, P.; Guilard, R.
Canadian Journal of Chemistry, 1995 , vol. 73, # 5 p. 685 - 695
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Barefield, E. Kent; Chueng, Duncan; Derveer, Donald G. Van; Wagner, Frank
Journal of the Chemical Society, Chemical Communications, 1981 , # 6 p. 302 - 304
反应条件
sodium tetrahydroborate in ethanol T=-10°C; 2 h;
参考文献
Chuburu, Francoise; Tripier, Raphael; Le Baccon, Michel; Handel, Henri
European Journal of Organic Chemistry, 2003 , # 6 p. 1050 - 1055
反应条件
2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; sodium t-butanolate; bis(dibenzylideneacetone)-palladium(0) in 1,4-dioxane Heating;
参考文献
Averin, Alexei D.; Shukhaev, Anton V.; Golub, Svetlana L.; Buryak, Alexei K.; Beletskaya, Irina P.
Synthesis, 2007 , # 19 p. 2995 - 3012
