(2R, 3S)-(-)-对甲氧苯基缩水甘油酸甲酯合成路线 （共 38 条）
反应条件
5A molecular sieve; Novozym 435 (Candida antarctica lipase, EC 3.1.1.3) in toluene T=20°C; Enzymatic reaction; Title compound not separated from byproducts.;
参考文献
Advanced Synthesis and Catalysis, , vol. 343, # 6-7 p. 721 - 725
反应条件
5A molecular sieve; Novozym 435 (Candida antarctica lipase, EC 3.1.1.3) in toluene T=20°C; Enzymatic reaction; Title compound not separated from byproducts.;
参考文献
Advanced Synthesis and Catalysis, , vol. 343, # 6-7 p. 721 - 725
反应条件
5A molecular sieve; Novozym 435 (Candida antarctica lipase, EC 3.1.1.3) in toluene T=20°C; Enzymatic reaction; Title compound not separated from byproducts.;
参考文献
Advanced Synthesis and Catalysis, , vol. 343, # 6-7 p. 721 - 725
反应条件
1: 1.17 g / zinc; acetic acid / 1.5 h / 20 °C 2: 894 mg / sodium methoxide / methanol / 0.75 h / 0 - 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 68, # 3 p. 974 - 979
反应条件
water in acetone T=25°C; Rhizopus arrhizus mycelium lipase, pH 7;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 32, # 1 p. 94 - 95
反应条件
water in toluene T=20°C; 72 h; Enzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 20, # 24 p. 2854 - 2860
反应条件
5A molecular sieve; Novozym 435 (Candida antarctica lipase, EC 3.1.1.3) in toluene T=20°C; 4 h; Enzymatic reaction; Product distributionEnzyme kinetics; Further Variations:SolventsReagentsReaction partners;
参考文献
Cantele, Francesca; Restelli, Angelo; Riva, Sergio; Tentorio, Dario; Villa, Marco
Advanced Synthesis and Catalysis, 2001 , vol. 343, # 6-7 p. 721 - 725
反应条件
1.1: 66 percent / KBrO3; aq. H2SO4; aq. NaHSO3 / acetonitrile / 36 h 2.1: 94 percent / DMAP / CH2Cl2 / 20 °C 3.1: lipase AS Amano; aq. phosphate buffer / toluene / 48 h / 30 °C / pH 7.0 3.2: lipase AS Amano; aq. phosphate buffer / toluene / 33 h / 30 °C / pH 7.0 4.1: HCl / methanol / 24 h / 20 °C 5.1: DBU / CH2Cl2 / 0.58 h / 5 - 20 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 15, # 19 p. 3131 - 3138
反应条件
Bacillus megaterium ECU1001 cell-free extract in potassium phosphate buffer; dimethyl sulfoxide T=30°C; pH=7; 0.0833333 h; Resolution of racemateEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 353, # 9 p. 1510 - 1518
反应条件
1: HCl / methanol / 24 h / 20 °C 2: DBU / CH2Cl2 / 0.58 h / 5 - 20 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 15, # 19 p. 3131 - 3138
