1,3beta,4alpha-三羟基-5-氧代环己烷-1beta-羧酸合成路线 （共 4 条）
反应条件
Amberlite IR 120 1.5 h; Heating;
参考文献
Journal of Chemical Research, Miniprint, , # 3 p. 532 - 544
反应条件
HCl buffer; type II dehydroquinase from M. tuberculosis; tri-(hydroxymethyl)-methylamine in water T=25°C; other reagent; Rate constant;
参考文献
Parker, Emily J.; Bello, Concepcion Gonzalez; Coggins, John R.; Hawkins, Alastair R.; Abell, Chris
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 3 p. 231 - 234
反应条件
1: 50 percent / Amberlite IR 120 / 1.5 h / Heating 2: Et3N / 18 h / 20 °C View Scheme
参考文献
Delfourne, Evelyne; Despeyroux, Pierre; Gorrichon, Liliane; Veronique, Jacqueline
Journal of Chemical Research, Miniprint, 1991 , # 3 p. 532 - 544
反应条件
Multi-step reaction with 4 steps 1: 81 percent / pyridinium chlorochromate; molecular sieves 4 Angstroem / CH2Cl2 / 15 h / 20 °C2: 83 percent / trifluoroacetic acid / H2O / 0.25 h / 0 °C3: 96 percent / KOH / H2O / 0.17 h / 20 °C4: 140 mg / amberlite IR-120 (H) / H2O / 0.08 h
参考文献
Le Sann, Christine; Abell, Chris; Abell, Andrew D. Synthetic Communications, 2003 , vol. 33, # 4 p. 527 - 533
