5-苯基-3-戊烯-2-酮合成路线 （共 7 条）
反应条件
in tetrahydrofuran T=20°C; 12 h;
参考文献
Zhang, Wei; Benmohamed, Radhia; Arvanites, Anthony C.; Morimoto, Richard I.; Ferrante, Robert J.; Kirsch, Donald R.; Silverman, Richard B.
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 2 p. 1029 - 1045
反应条件
in tetrahydrofuran T=20°C; Wittig Olefination; Reflux;
参考文献
Ning, Xianling; Guo, Ying; Ma, Xiaoyan; Zhu, Renzong; Tian, Chao; Wang, Xiaowei; Ma, Zhizhong; Zhang, Zhili; Liu, Junyi
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 13 p. 3700 - 3703
反应条件
n-butyllithium; hydrogen fluoride 1.) THF; Multistep reaction;
参考文献
Cristau, Henri-Jean; Torreilles, Eliane; Barois-Gacherieu, Catherine
Synthetic Communications, 1988 , vol. 18, # 2 p. 185 - 190
反应条件
(i) LDA, (ii) /BRN= 385801/, (iii) aq. H2O2, CH2Cl2, Py; Multistep reaction;
参考文献
Reich,H.J.
Journal of Organic Chemistry, 1975 , vol. 40, # 17 p. 2570 - 2572
反应条件
methanol; water; oxygen; toluene-4-sulfonic acid; palladium dichloride in N,N-dimethyl acetamide T=80°C; P=4560.31 Torr; 40 h; Autoclave; regioselective reaction;
参考文献
Mitsudome, Takato; Yoshida, Syuhei; Mizugaki, Tomoo; Jitsukawa, Koichiro; Kaneda, Kiyotomi
Angewandte Chemie - International Edition, 2013 , vol. 52, # 23 p. 5961 - 5964
Angew. Chem., 2013 , vol. 125, # 23 p. 6077 - 6080,4
反应条件
palladium 10 on activated carbon; hydrogen in dichloromethane
T=20°C;
参考文献
Ning, Xianling; Guo, Ying; Ma, Xiaoyan; Zhu, Renzong; Tian, Chao; Wang, Xiaowei; Ma, Zhizhong; Zhang, Zhili; Liu, Junyi
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 13 p. 3700 - 3703
反应条件
1: With sodium ethanolate in ethanol
12 h;
2: With sodium hydroxide in ethanol; water
12 h;
3: With hydrogenchloride in diethyl ether; water
参考文献
Zhang, Wei; Benmohamed, Radhia; Arvanites, Anthony C.; Morimoto, Richard I.; Ferrante, Robert J.; Kirsch, Donald R.; Silverman, Richard B.
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 2 p. 1029 - 1045
