(2-氨基-5-氯苯基)-3-吡啶甲酮合成路线 （共 6 条）
反应条件
sulfuric acid T=95 - 100°C;
参考文献
Kyba, Evan P.; Liu, Shiuh-Tzung; Chockalingam, Kannappan; Reddy, B. Raghava
Journal of Organic Chemistry, 1988 , vol. 53, # 15 p. 3513 - 3521
反应条件
aluminium trichloride; boron trichloride in various solvent(s) RT, 20 min; reflux, 6 h;
参考文献
Earley, James V.; Gilman, Norman W.
Synthetic Communications, 1985 , vol. 15, # 14 p. 1271 - 1276
反应条件
2: 71 percent / 70percent aq. sulfuric acid / 95 - 100 °C View Scheme
参考文献
Kyba, Evan P.; Liu, Shiuh-Tzung; Chockalingam, Kannappan; Reddy, B. Raghava
Journal of Organic Chemistry, 1988 , vol. 53, # 15 p. 3513 - 3521
反应条件
2: 71 percent / 70percent aq. sulfuric acid / 95 - 100 °C View Scheme
参考文献
Kyba, Evan P.; Liu, Shiuh-Tzung; Chockalingam, Kannappan; Reddy, B. Raghava
Journal of Organic Chemistry, 1988 , vol. 53, # 15 p. 3513 - 3521
反应条件
sulfuric acid; urea; sodium nitrite 1.) a.) water, from 0 to 5 deg C, 2.) 30 deg C, irradiation, 2 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Kyba, Evan P.; Liu, Shiuh-Tzung; Chockalingam, Kannappan; Reddy, B. Raghava
Journal of Organic Chemistry, 1988 , vol. 53, # 15 p. 3513 - 3521
反应条件
sulfuric acid; urea; sodium nitrite 1.) a.) water, from 0 to 5 deg C, 2.) 30 deg C, irradiation, 2 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Kyba, Evan P.; Liu, Shiuh-Tzung; Chockalingam, Kannappan; Reddy, B. Raghava
Journal of Organic Chemistry, 1988 , vol. 53, # 15 p. 3513 - 3521
