thionyl chloride in chloroform; N,N-dimethyl-formamide 4 h; Heating;

potassium carbonate in N,N-dimethyl-formamide 1.5 h; Ambient temperature;

1: 1) NaH / 1) DMF, 6 h, 2) ambient temp., 16 h 2: 42 percent / trifluoroacetic acid / 16 h / Heating 3: 24 percent / NaOMe / dimethylformamide / 24 h / Heating 4: 54 percent / SOCl2 / CHCl3; dimethylformamide / 4 h / Heating View Scheme

1: 42 percent / trifluoroacetic acid / 16 h / Heating 2: 24 percent / NaOMe / dimethylformamide / 24 h / Heating 3: 54 percent / SOCl2 / CHCl3; dimethylformamide / 4 h / Heating View Scheme

in ethanol 16 h; Ambient temperature;