3-(3-甲氧基苯基)丙酸合成路线 （共 43 条）
反应条件
hydrogen; palladium hydroxide - carbon in tetrahydrofuran; ethanol P=760 Torr; Ambient temperature;
参考文献
Belletire, J. L.; Fremont, S. L.
Tetrahedron Letters, 1986 , vol. 27, # 2 p. 127 - 130
反应条件
1: 94.8 percent / pyridine, piperidine 2: 96.3 percent / H2 / 10percent Pd/C / methanol View Scheme
参考文献
Journal of Organic Chemistry, , vol. 54, # 18 p. 4298 - 4301
反应条件
1.1: n-BuLi; NaH / tetrahydrofuran; hexane / 0.33 h / 0 °C 1.2: tetrahydrofuran; hexane / 2 h 2.1: 80 percent / ceric ammonium nitrate / acetonitrile / 4 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 71, # 12 p. 4516 - 4520
参考文献
Journal of the American Chemical Society, , vol. 71, p. 1092,1095
Journal of the American Chemical Society, , vol. 71, p. 3523,3527
反应条件
1: methanol; KOH / 100 °C / im geschlossenen Rohr und Erhitzen des entstandenen Esters mit verd. Kalilauge 2: water; sodium amalgam View Scheme
参考文献
Chemische Berichte, , vol. 15, p. 2055
反应条件
Tb(OTf)3 in chlorobenzene T=250°C; Friedel-Crafts reaction; 3 h;
参考文献
Tetrahedron Letters, , vol. 45, # 8 p. 1741 - 1745
参考文献
Journal of Organic Chemistry, , vol. 33, # 6 p. 2457 - 2462
反应条件
1: LiAlH4 / tetrahydrofuran 2: HBr 5: n-Bu4NF / hexamethylphosphoric acid triamide / 2 h / 40 °C 6: 1 M HCl / acetone / 1.5 h / Ambient temperature 7: 30 percent / 0.5 M Na2CO3, 0.5 M K3Fe(CN)6 / 3 h at 0 deg C, then 14 h at 25 deg C View Scheme
参考文献
Leboff, A.; Carbonelle, A.-C.; Alazard, J.-P.; Thal, C.; Kende, A. S.
Tetrahedron Letters, 1987 , vol. 28, # 36 p. 4163 - 4164
反应条件
H4SiW12O40 in chlorobenzene Friedel-Crafts acylation; Heating;
参考文献
Lan, Kun; Shan, Zi-Xing
Synthetic Communications, 2007 , vol. 37, # 13 p. 2171 - 2177
反应条件
Tb(OTf)3 in chlorobenzene T=250°C; Friedel-Crafts reaction; 3 h;
参考文献
Barlow, James W.; Walsh, John J.
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 1 p. 25 - 37
