4-硝基苯基N-((苄氧基)羰基)-L-缬氨酸酯合成路线 （共 16 条）
反应条件
n-ethyl morpholine; hexamethylphosphorous triamide dichloride in dichloromethane 1) 0 deg C, 2 h, 2) overnight, r.t.;
参考文献
Appel, Rolf; Glaesel, Ursula
Chemische Berichte, 1980 , vol. 113, # 11 p. 3511 - 3516
反应条件
1: thionyl chloride; diethyl ether; pyridine 2: pyridine View Scheme
参考文献
Helvetica Chimica Acta, , vol. 40, p. 373,385
参考文献
Helvetica Chimica Acta, , vol. 40, p. 373,385
反应条件
(i) DMF, (ii) /BRN= 2056617/, Et3N; Multistep reaction;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 18, # 4 p. 784 - 788
反应条件
benzotriazol-1-ol in acetonitrile
参考文献
Zvilichovsky, Gury; Gbara-Haj-Yahia, Isra
Journal of Organic Chemistry, 2004 , vol. 69, # 15 p. 4966 - 4973
反应条件
sodium hydroxide in water; butan-1-ol Ambient temperature;
参考文献
Litvinenko, L. M.; Kosmynin, V. V.; Kaida, L. N.; Savelova, V. A.; Verbovaya, I. P.
Journal of Organic Chemistry USSR (English Translation), 1986 , vol. 22, # 4 p. 784 - 785
Zhurnal Organicheskoi Khimii, 1986 , vol. 22, # 4 p. 877 - 878
反应条件
in tetrahydrofuran 24 h;
参考文献
Kempf, Dale J.; Codacovi, Lynnmarie; Wang, Xiu Chun; Kohlbrenner, William E.; Wideburg, Norman E.; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 3 p. 320 - 330
反应条件
in tetrahydrofuran 24 h;
参考文献
Kempf, Dale J.; Codacovi, Lynnmarie; Wang, Xiu Chun; Kohlbrenner, William E.; Wideburg, Norman E.; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 3 p. 320 - 330
反应条件
in tetrahydrofuran 24 h;
参考文献
Journal of Medicinal Chemistry, , vol. 36, # 3 p. 320 - 330
反应条件
N-hexadecyl-N,N,N-trimethylammonium bromide; Dec-L-His in acetonitrile T=25°C; 0.02M phosphate buffer, pH=7.3; other catalysts; Rate constant;
参考文献
Ascenzi, Paolo; Sleiter, Giancarlo; Antonini, Eraldo
Gazzetta Chimica Italiana, 1982 , vol. 112, # 7/8 p. 307 - 318
