N-[(2S)-3-甲基-1-氧代-1-[2-[[(3S)-1,1,1-三氟-4-甲基-2-氧代戊烷-3-基]氨基甲酰]吡咯烷-1-基]丁烷-2-基]氨基甲酸苯甲酯合成路线 （共 5 条）
反应条件
dichloro-acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dimethyl sulfoxide; toluene
参考文献
Edwards, Philip D.
Tetrahedron Letters, 1992 , vol. 33, # 30 p. 4279 - 4282
反应条件
1: i-BuOCOCl, NMM 2: 1.) Swern 2.) H(1+) 3: activated zinc / dimethylformamide / 1 h / -20 °C 4: 70 percent / dichloroacetic acid, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride / dimethylsulfoxide; toluene View Scheme
参考文献
Edwards, Philip D.
Tetrahedron Letters, 1992 , vol. 33, # 30 p. 4279 - 4282
反应条件
1: LiAlH4 2: i-BuOCOCl, NMM 3: 1.) Swern 2.) H(1+) 4: activated zinc / dimethylformamide / 1 h / -20 °C 5: 70 percent / dichloroacetic acid, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride / dimethylsulfoxide; toluene View Scheme
参考文献
Edwards, Philip D.
Tetrahedron Letters, 1992 , vol. 33, # 30 p. 4279 - 4282
反应条件
1: 1.) Swern 2.) H(1+) 2: activated zinc / dimethylformamide / 1 h / -20 °C 3: 70 percent / dichloroacetic acid, 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride / dimethylsulfoxide; toluene View Scheme
参考文献
Edwards, Philip D.
Tetrahedron Letters, 1992 , vol. 33, # 30 p. 4279 - 4282
反应条件
dichloro-acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; zinc multistep reaction; stereoselective synthesis; other educt;
参考文献
Edwards, Philip D.
Tetrahedron Letters, 1992 , vol. 33, # 30 p. 4279 - 4282
