1-甲基-1H-1,2,3-噻唑-5-羧酸甲酯合成路线 （共 17 条）
反应条件
in tetrahydrofuran; diethyl ether T=20°C; 16 h;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; LLINAS-BRUNET, Montse; BORDELEAU , Josee; GODBOUT, Cedrickx; LEBLANC, Melissa; MOREAU, Benoit; O'MEARA, Jeffrey
Patent: WO2011/63501 A1, 2011 ;
Location in patent: Page/Page column 33 ;
WO 2011/063501 A1
反应条件
in toluene 16 h; Heating / reflux;
参考文献
SYNGENTA LIMITED
Patent: WO2007/96576 A1, 2007 ;
Location in patent: Example I19 ;
反应条件
in tetrahydrofuran T=20°C; 26 h; Further byproducts given;
参考文献
Huisgen, Rolf; Mitra, Abhijit; Moran, Joaquin Rodriguez
Heterocycles, 1986 , vol. 24, # 9 p. 2429 - 2436
反应条件
caesium carbonate in 1-methyl-pyrrolidin-2-one T=0°C; 1 h; Inert atmosphere;
参考文献
Prabakaran; Khan, Fazlur-Rahman Nawaz; Jin, Jong Sung
Research on Chemical Intermediates, 2012 , vol. 38, # 3-5 p. 1101 - 1109
反应条件
nitrogen in tetrahydrofuran 4 h; Ambient temperature;
参考文献
Huisgen, Rolf; Mitra, Abhijit; Moran, Joaquin Rodriguez
Heterocycles, 1986 , vol. 24, # 9 p. 2429 - 2436
反应条件
in tetrahydrofuran T=20°C; 96 h; Further byproducts given;
参考文献
Huisgen, Rolf; Mitra, Abhijit; Moran, Joaquin Rodriguez
Heterocycles, 1986 , vol. 24, # 9 p. 2429 - 2436
反应条件
in tetrahydrofuran T=20°C; 26 h; Further byproducts given;
参考文献
Huisgen, Rolf; Mitra, Abhijit; Moran, Joaquin Rodriguez
Heterocycles, 1986 , vol. 24, # 9 p. 2429 - 2436
反应条件
in tetrahydrofuran T=20°C; 26 h;
参考文献
Huisgen, Rolf; Mitra, Abhijit; Moran, Joaquin Rodriguez
Heterocycles, 1986 , vol. 24, # 9 p. 2429 - 2436
反应条件
in tetrahydrofuran T=20°C; 96 h; Further byproducts given;
参考文献
Huisgen, Rolf; Mitra, Abhijit; Moran, Joaquin Rodriguez
Heterocycles, 1986 , vol. 24, # 9 p. 2429 - 2436
反应条件
in tetrahydrofuran T=20°C; 96 h; Further byproducts given;
参考文献
Huisgen, Rolf; Mitra, Abhijit; Moran, Joaquin Rodriguez
Heterocycles, 1986 , vol. 24, # 9 p. 2429 - 2436
