3-氨基-6-苯基-4-(三氟甲基)噻吩[2,3-B]吡啶-2-甲腈合成路线 （共 5 条）
反应条件
potassium hydroxide in N,N-dimethyl-formamide T=20°C; 0.5 h;
参考文献
Rodinovskaya, L. A.; Sharanin, Yu. A.; Litvinov, V. P.; Shestopalov, A. M.; Promonenkov, V. K.; et al.
Journal of Organic Chemistry USSR (English Translation), 1985 , vol. 21, # 11 p. 2230 - 2235
Zhurnal Organicheskoi Khimii, 1985 , vol. 21, # 11 p. 2439 - 2444
反应条件
potassium hydroxide in N,N-dimethyl-formamide 0.5 h;
参考文献
Rodinovskaya, L. A.; Sharanin, Yu. A.; Litvinov, V. P.; Shestopalov, A. M.; Promonenkov, V. K.; et al.
Journal of Organic Chemistry USSR (English Translation), 1985 , vol. 21, # 11 p. 2230 - 2235
Zhurnal Organicheskoi Khimii, 1985 , vol. 21, # 11 p. 2439 - 2444
反应条件
1: 84 percent / triethylamine / ethanol / 24 h / 20 °C 2: 81 percent / 10percent aq. KOH / dimethylformamide / 0.5 h View Scheme
参考文献
Rodinovskaya, L. A.; Sharanin, Yu. A.; Litvinov, V. P.; Shestopalov, A. M.; Promonenkov, V. K.; et al.
Journal of Organic Chemistry USSR (English Translation), 1985 , vol. 21, # 11 p. 2230 - 2235
Zhurnal Organicheskoi Khimii, 1985 , vol. 21, # 11 p. 2439 - 2444
反应条件
1: 88 percent / ethanol / 24 h / 25 - 30 °C 2: 81 percent / 10percent aq. KOH / dimethylformamide / 0.5 h View Scheme
参考文献
Rodinovskaya, L. A.; Sharanin, Yu. A.; Litvinov, V. P.; Shestopalov, A. M.; Promonenkov, V. K.; et al.
Journal of Organic Chemistry USSR (English Translation), 1985 , vol. 21, # 11 p. 2230 - 2235
Zhurnal Organicheskoi Khimii, 1985 , vol. 21, # 11 p. 2439 - 2444
反应条件
1: 47 percent / 10percent aq. KOH / dimethylformamide 2: 87 percent / 10percent aq. KOH / dimethylformamide / 0.5 h / 20 °C View Scheme
参考文献
Rodinovskaya, L. A.; Sharanin, Yu. A.; Litvinov, V. P.; Shestopalov, A. M.; Promonenkov, V. K.; et al.
Journal of Organic Chemistry USSR (English Translation), 1985 , vol. 21, # 11 p. 2230 - 2235
Zhurnal Organicheskoi Khimii, 1985 , vol. 21, # 11 p. 2439 - 2444
