4-溴-1,1,2-三氟-1-丁烯合成路线 （共 10 条）
反应条件
potassium carbonate in acetonitrile 6 h; Heating / reflux;
参考文献
Bayer CropScience K.K.
Patent: EP1200418 B1, 2004 ;
Location in patent: Page 9 ;
反应条件
bromine chloride in dichloromethane T=25°C; 15 h; Further byproducts.;
参考文献
Shellhamer, Dale F.; Davenport, Kevyn J.; Forberg, Heidi K.; Herrick, Matthew P.; Jones, Rachel N.; Rodriguez, Sean J.; Sanabria, Sunamita; Trager, Nicole N.; Weiss, Ryan J.; Heasley, Victor L.; Boatz, Jerry A.
Journal of Organic Chemistry, 2008 , vol. 73, # 12 p. 4532 - 4538
反应条件
bromine in dichloromethane T=20°C; 1 h;
参考文献
Ehm, Christian; Akkerman, Floris A.; Lentz, Dieter
Journal of Fluorine Chemistry, 2010 , vol. 131, # 11 p. 1173 - 1181
反应条件
Iodine bromide in dichloromethane T=25°C; 12 h;
参考文献
Shellhamer, Dale F.; Davenport, Kevyn J.; Forberg, Heidi K.; Herrick, Matthew P.; Jones, Rachel N.; Rodriguez, Sean J.; Sanabria, Sunamita; Trager, Nicole N.; Weiss, Ryan J.; Heasley, Victor L.; Boatz, Jerry A.
Journal of Organic Chemistry, 2008 , vol. 73, # 12 p. 4532 - 4538
参考文献
Shellhamer, Dale F.; Allen, Jeannette L.; Allen, Rachel D.; Gleason, David C.; Schlosser, Colleen O'Neil; Powers, Benjamin J.; Probst, John W.; Rhodes, Michelle C.; Ryan, Andrew J.; Titterington, Peter K.; Vaughan, Gregory Gawayne; Heasley, Victor L.
Journal of Organic Chemistry, 2003 , vol. 68, # 10 p. 3932 - 3937
参考文献
Muramatsu,H.; Tarrant,P.
Journal of Organic Chemistry, 1964 , vol. 29, p. 1796 - 1800
反应条件
hydrogenchloride; sodium hydroxide; magnesium in diethyl ether
参考文献
FMC Corporation
Patent: US4952580 A1, 1990 ;
反应条件
HBr gas; sodium hydrogencarbonate in dichloromethane
参考文献
Zeneca Limited
Patent: US5728833 A1, 1998 ;
反应条件
bromine chloride in dichloromethane
T=25°C; 15 h; Further byproducts.;
参考文献
Shellhamer, Dale F.; Davenport, Kevyn J.; Forberg, Heidi K.; Herrick, Matthew P.; Jones, Rachel N.; Rodriguez, Sean J.; Sanabria, Sunamita; Trager, Nicole N.; Weiss, Ryan J.; Heasley, Victor L.; Boatz, Jerry A.
Journal of Organic Chemistry, 2008 , vol. 73, # 12 p. 4532 - 4538
反应条件
potassium hydroxide; tetrabutylammomium bromide in xylene
T=60°C; 5 h;
参考文献
The University of Rochester
Patent: US4902835 A1, 1990 ;
