N-叔丁基-2-甲基苯甲酰胺合成路线 （共 9 条）
反应条件
triethylamine in dichloromethane; water
参考文献
Eli Lilly and Company
Patent: US5554653 A1, 1996 ;
反应条件
air; 1,8-diazabicyclo[5.4.0]undec-7-ene; palladium diacetate in tetrahydrofuran T=100°C; 0.25 h; mocrowaver irradiation;
参考文献
Wannberg, Johan; Larhed, Mats
Journal of Organic Chemistry, 2003 , vol. 68, # 14 p. 5750 - 5753
反应条件
N,N,N',N,-tetramethylethylenediamine; sec.-butyllithium in tetrahydrofuran
参考文献
Eli Lilly and Company
Patent: US5491166 A1, 1996 ;
反应条件
air; 1,8-diazabicyclo[5.4.0]undec-7-ene; trans-di(μ-acetato)bis[o-(di-o-tolylphosphino)benzyl]dipalladium(II) in tetrahydrofuran T=150°C; 0.25 h;
参考文献
Wannberg, Johan; Larhed, Mats
Journal of Organic Chemistry, 2003 , vol. 68, # 14 p. 5750 - 5753
反应条件
N,N,N',N,-tetramethylethylenediamine; ammonium chloride in tetrahydrofuran; dichloromethane; ethyl acetate
参考文献
ELI LILLY AND COMPANY; ATHENA NEUROSCIENCES, INC.
Patent: EP652009 A1, 1995 ;
EP 0652009 A1
反应条件
sulfuric acid in acetic acid T=45°C; Ritter reaction; 0.1 h;
参考文献
Audiger, Logan; Watts, Kevin; Elmore, Simon C.; Robinson, Richard I.; Wirth, Thomas
ChemSusChem, 2012 , vol. 5, # 2 p. 257 - 260
反应条件
bismuth trifluoromethanesulphonate; water T=100°C; Ritter reaction;
参考文献
Callens, Emmanuel; Burton, Andrew J.; Barrett, Anthony G.M.
Tetrahedron Letters, 2006 , vol. 47, # 49 p. 8699 - 8701
反应条件
water; sodium 1.) THF,HMPA, RT, sonication; Yield given. Multistep reaction;
参考文献
Einhorn, J.; Luche, J. L.
Tetrahedron Letters, 1986 , vol. 27, # 4 p. 501 - 504
反应条件
1: 0.33 g / t-BuOBr 2: 0.13 g / benzene / 1 h / 20 °C / Irradiation 3: 0.07 g / Na2CO3 4: 0.03 g / 20percent H2SO4 / 3 h / Heating View Scheme
参考文献
Chow, Yuan L.; Mojelsky, Thomas W.; Magdzinski, Leon J.; Tichy, M.
Canadian Journal of Chemistry, 1985 , vol. 63, p. 2197 - 2202
