2-氧代环戊烷羧酸甲酯合成路线 （共 119 条）
反应条件
hydrogenchloride; copper(ll) bromide; lithium diisopropyl amide in tetrahydrofuran; hexane 1.) -78 deg C, 30 min; -78 deg C, 15 min, 2.) RT;
参考文献
Chung, Sung Kee; Dunn, Larson B.
Journal of Organic Chemistry, 1983 , vol. 48, # 7 p. 1125 - 1127
反应条件
1: cyclopentanone With lithium hexamethyldisilazane in tetrahydrofuran T=-78 - -20°C; 1 h; 2: methoxycarbonyl cyanide in tetrahydrofuran T=-78°C; 0.166667 h; 3: With ammonium chloride in tetrahydrofuran; water T=-78°C;
参考文献
European Journal of Medicinal Chemistry, , vol. 46, # 11 p. 5549 - 5555
反应条件
poly(dimethylsiloxane-co-methylhydrosiloxane)trimethylsilyl terminated supported 1-carboxy-6-ethyl-1,8-diazabicyclo[5.4.0]undec-7-ene in methanol T=25 - 27°C; P=760.051 Torr; 4 h;
参考文献
Beckman, Eric J.; Munshi, Pradip
Green Chemistry, 2011 , vol. 13, # 2 p. 376 - 383
反应条件
samarium diiodide in tetrahydrofuran; N,N,N',N',N'',N''-hexamethylphosphoric triamide T=0°C;
参考文献
Hong, Xuechuan; Mejia-Oneto, Jose M.; Padwa, Albert
Tetrahedron Letters, 2006 , vol. 47, # 47 p. 8387 - 8390
反应条件
samarium diiodide; mercury; zinc in tetrahydrofuran T=23°C; 7 h;
参考文献
Corey; Zheng, Guo Zhu
Tetrahedron Letters, 1997 , vol. 38, # 12 p. 2045 - 2048
反应条件
1: carbonic acid dimethyl ester With potassium tert-butylate; sodium hydride in tetrahydrofuran Inert atmosphere; 2: cyclopentanone in tetrahydrofuran T=20°C; 5 h; Inert atmosphere;
参考文献
Vita, Maria Victoria; Waser, Jerome
Organic Letters, 2013 , vol. 15, # 13 p. 3246 - 3249
反应条件
methyl chloroformate in water; toluene 1.) toluene, reflux, 6 h, 2.) water, reflux, 1 h;
参考文献
Jones,R.A.; Stokes,M.J.
Tetrahedron, 1984 , vol. 40, p. 1051
反应条件
potassium tert-butylate in dimethyl sulfoxide 3 h; Ambient temperature;
参考文献
Xie, Zhuo-Feng; Suemune, Hiroshi; Sakai, Kiyoshi
Synthetic Communications, 1989 , vol. 19, # 5and6 p. 987 - 992
反应条件
potassium tert-butylate in dimethyl sulfoxide 3 h; Ambient temperature;
参考文献
Xie, Zhuo-Feng; Suemune, Hiroshi; Sakai, Kiyoshi
Synthetic Communications, 1989 , vol. 19, # 5and6 p. 987 - 992
反应条件
1-ethyl-piperidine; TiCl2(OTf)2 in dichloromethane T=-23°C; 3 h;
参考文献
Tanabe, Yoo; Mukaiyama, Teruaki
Chemistry Letters, 1986 , p. 1813 - 1816
