2-[(3-氧代-1-环己烯-1-基)氨基]苯甲腈合成路线 (共 4 条)
反应条件
toluene-4-sulfonic acid in toluene 2 h; Heating;
参考文献
Shutske; Pierrat; Kapples; Cornfeldt; Szewczak; Huger; Bores; Haroutunian; Davis
Journal of Medicinal Chemistry, 1989 , vol. 32, # 8 p. 1805 - 1813
参考文献
Hoechst Celanese Corporation
Patent: US5247091 A1, 1993 ;
反应条件
1: 62.3 percent / K2CO3 / CuCl / tetrahydrofuran / 5 h / Heating 2: 41 percent / NaOH / <n-Bu4N><HSO4> / CH2Cl2; H2O / 4 h View Scheme
参考文献
Shutske; Pierrat; Kapples; Cornfeldt; Szewczak; Huger; Bores; Haroutunian; Davis
Journal of Medicinal Chemistry, 1989 , vol. 32, # 8 p. 1805 - 1813
反应条件
potassium carbonate; copper(l) chloride in tetrahydrofuran 5 h; Heating;
参考文献
Shutske; Pierrat; Kapples; Cornfeldt; Szewczak; Huger; Bores; Haroutunian; Davis
Journal of Medicinal Chemistry, 1989 , vol. 32, # 8 p. 1805 - 1813