(R)-(-)-1-甲基-3-羟基吡咯烷合成路线 （共 3 条）
反应条件
formic acid in tetrahydrofuran 5 h; Heating / reflux;
参考文献
Bodor, Nicholas S.
Patent: US2007/123557 A1, 2007 ;
Location in patent: Page/Page column 16 ;
US 20070123557 A1
反应条件
sodium hydroxide; formic acid in tetrahydrofuran; water T=60°C; 2.33333 h; Heating / reflux;
参考文献
Wu; Mori; Buchwald; Bodor, Nicholas
Pharmazie, 2008 , vol. 63, # 3 p. 200 - 209
反应条件
sodium bis(2-methoxyethoxy)aluminium dihydride in tetrahydrofuran; toluene 1 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 34, # 4 p. 1314 - 1328
