2-羟基-2-(2-萘基)丙酸合成路线 （共 9 条）
反应条件
lithium hydroxide in tetrahydrofuran
参考文献
Posakony, Jeff; Hirao, Maki; Stevens, Sam; Simon, Julian A.; Bedalov, Antonio
Journal of Medicinal Chemistry, 2004 , vol. 47, # 10 p. 2635 - 2644
参考文献
Cano, Marisol; Rojas, Carlos; Hidalgo, William; Saez, Jairo; Gil, Jesus; Schneider, Bernd; Otalvaro, Felipe
Tetrahedron Letters, 2013 , vol. 54, # 4 p. 351 - 354
反应条件
potassium hydroxide in ethanol 2 h; Ambient temperature;
参考文献
Panetta, Jill A.; Rapoport, Henry
Journal of Organic Chemistry, 1982 , vol. 47, # 6 p. 946 - 950
反应条件
1: 94 percent / pivalic acid / toluene / 20 h / Heating 2: 10percent aq.HCl / diethyl ether / 2 h / Ambient temperature 3: 85 percent / KOH / ethanol / 2 h / Ambient temperature View Scheme
参考文献
Lichtenberger,J. et al.
Bulletin de la Societe Chimique de France, 1962 , p. 997 - 1001
反应条件
1: 10percent aq.HCl / diethyl ether / 2 h / Ambient temperature 2: 85 percent / KOH / ethanol / 2 h / Ambient temperature View Scheme
参考文献
Panetta, Jill A.; Rapoport, Henry
Journal of Organic Chemistry, 1982 , vol. 47, # 6 p. 946 - 950
反应条件
sodium hydroxide; nickel monoaluminide T=80 - 90°C; 1 h;
参考文献
Ranade, Anup A.; Joseph, Augustine R.; Kumbhar, Virendra B.; Paradkar, Madhusudan V.
Journal of Chemical Research, Miniprint, 2003 , # 11 p. 1175 - 1184
反应条件
1: NaOH / benzene / Heating 2: (alkaline hydrolysis) View Scheme
参考文献
Lichtenberger,J. et al.
Bulletin de la Societe Chimique de France, 1962 , p. 997 - 1001
反应条件
palladium on activated charcoal in diphenylether 20 h; Heating;
参考文献
Panetta, Jill A.; Rapoport, Henry
Journal of Organic Chemistry, 1982 , vol. 47, # 6 p. 946 - 950
参考文献
Ranade, Anup A.; Joseph, Augustine R.; Kumbhar, Virendra B.; Paradkar, Madhusudan V.
Journal of Chemical Research, Miniprint, 2003 , # 8 p. 857 - 868
