in tetrahydrofuran; water; acetone T=0 - 20°C; 2 h;

triethylamine in acetonitrile 0.166667 h; Ambient temperature;

triethylamine in acetonitrile 0.166667 h; Ambient temperature;

1: benzyl-methyl-amine With ethyl-α,α,α-trifluoroacetate T=0 - 22°C; 0.5 h; 2: (S)-2-[N-(t-butoxycarbonyl)amino]-3-(naphth-2-yl)-propionic acid With 4-methyl-morpholine in ethyl acetate T=-15°C; 0.25 h; 3: isobutyl chloroformate in ethyl acetate T=-15°C; 1 h;

1: 99 percent / pyridine / 1 h / Ambient temperature 2: 90 percent / triethylamine / acetonitrile / 0.17 h / Ambient temperature View Scheme

in dichloromethane; water