2-氰基-N-(苯基甲基)-乙酰胺合成路线 （共 19 条）
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in 2-methyl tetrahydrofuran T=20°C; 12 h;
参考文献
Price, Kristin E.; Larrivee-Aboussafy, Claude; Lillie, Brett M.; McLaughlin, Robert W.; Mustakis, Jason; Hettenbach, Kevin W.; Hawkins, Joel M.; Vaidyanathan, Rajappa
Organic Letters, 2009 , vol. 11, # 9 p. 2003 - 2006
反应条件
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide T=20°C;
参考文献
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; Taunton, JR., John William; Maglathlin, Rebecca; Serafimova, Iana; Cohen, Michael S.; Miller, Rand; Paavilainen, Ville; McFarland, Jesse; Krishnan, Shyam
Patent: US2013/35325 A1, 2013 ;
Location in patent: Paragraph 0302; 0303 ;
反应条件
in N,N-dimethyl-formamide T=135°C; 0.5 h; Microwave irradiation;
参考文献
Guo, Diliang; Chen, Tao; Ye, Deju; Xu, Jinyi; Jiang, Hualiang; Chen, Kaixian; Wang, Hui; Liu, Hong
Organic Letters, 2011 , vol. 13, # 11 p. 2884 - 2887
反应条件
in toluene 0.0166667 h; Heating;
参考文献
Gorobets, Nikolay Yu.; Yousefi, Behrooz H.; Belaj, Ferdinand; Kappe, C. Oliver
Tetrahedron, 2004 , vol. 60, # 39 p. 8633 - 8644
参考文献
Chem. Zentralbl., , vol. 72, # I p. 578
反应条件
in decane T=20°C; Substitution; butylaminolysis; KineticsThermodynamic data; Further Variations:Temperatures;
参考文献
Journal of Physical Organic Chemistry, , vol. 12, # 10 p. 747 - 750
反应条件
hydrogen sulfide; triethylamine in ethanol T=70°C; 1.5 h;
参考文献
Morzherin; Kosterina; Berseneva; Dehaen; Bakulev
Russian Chemical Bulletin, 2002 , vol. 51, # 7 p. 1292 - 1297
参考文献
Gazit, Aviv; Osherov, Nir; Posner, Israel; Yaish, Pnina; Poradosu, Enrique; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 6 p. 1896 - 1907
反应条件
piperidine in ethanol
T=20°C; Knoevenagel condensation; 1 h;
参考文献
HSC RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP
Patent: WO2005/92904 A1, 2005 ;
Location in patent: Page/Page column 122-123 ;
反应条件
sodium hydroxide in toluene
T=0°C; 0.166667 h;
参考文献
Andreae, Siegfried; Schmitz, Ernst; Wulf, Jens-Peter; Schulz, Burkhard
Liebigs Annalen der Chemie, 1992 , # 3 p. 239 - 256
