甲基(15E)-15-十八碳烯酸酯合成路线 (共 1 条)
反应条件
1: (n-propyl)-triphenylphosphonium bromide With sodium hexamethyldisilazane in tetrahydrofuran T=0 - 20°C; Wittig reaction; Inert atmosphere; 2: 15-oxo-pentadecanoic acid methyl ester in tetrahydrofuran T=-78 - 20°C; Wittig reaction; Inert atmosphere; stereoselective reaction;
参考文献
Rawling, Tristan; Duke, Colin C.; Cui, Pei H.; Murray, Michael
Lipids, 2010 , vol. 45, # 2 p. 159 - 165