反应条件
1: 1.) Mg, 1,2-dibromoethane / 1.) THF, RT, 30 min, 2.) THF, from -40 deg C to RT, overnight 2: H2, AcOH / 10 percent Pd/C / ethanol View Scheme
参考文献
Zhou, Zhang-Lin; Cai, Sui Xiong; Whittemore, Edward R.; Konkoy, Christopher S.; Espitia, Stephen A.; Tran, Minhtam; Rock, David M.; Coughenour, Linda L.; Hawkinson, Jon E.; Boxer, Peter A.; Bigge, Christopher F.; Wise, Lawrence D.; Weber, Eckard; Woodward, Richard M.; Keana, John F. W.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 15 p. 2993 - 3000
