1: 89 percent / Bu4NF / tetrahydrofuran 2: 82 percent / pyridine / 3 h / Ambient temperature View Scheme

1.1: 98 percent / NaH / tetrahydrofuran / 2 h / 20 °C 2.1: 84 percent / Bu3SnH; AIBN / toluene / 5 h / Heating 3.1: 81 percent / 1M Bu4NF / tetrahydrofuran / 4 h / 20 °C 4.1: 92 percent / Et3N / CH2Cl2 / 20 °C 5.1: 85 percent / NaN3 / dimethylformamide / 12 h / 85 °C 6.1: Acid hydrolysis 7.1: imidazole; Et3N / CH2Cl2 / 0.75 h 8.1: 72 percent / (COCl)2; DMSO; Et3N / 2 h 9.1: aq. HF / 20 °C 9.2: H2 / 10percent Pd/C / methanol / 2 h / 760.05 Torr View Scheme