N-[1-(4-氟苯基)丙-2-基]-N-甲基丙-2-炔-1-胺合成路线 （共 3 条）
反应条件
sodium cyanoborohydride in water; acetonitrile 0.25 h; Ambient temperature;
参考文献
Plenevaux; Dewey; Fowler; Guillaume; Wolf
Journal of Medicinal Chemistry, 1990 , vol. 33, # 7 p. 2015 - 2019
反应条件
1: 52 percent / LiAlH4 / tetrahydrofuran / 4 h / Ambient temperature 2: 62 percent / K2CO3 / acetonitrile; toluene; H2O 3: 93 percent / NaBH3CN / acetonitrile; H2O / 0.25 h / Ambient temperature View Scheme
参考文献
Plenevaux; Dewey; Fowler; Guillaume; Wolf
Journal of Medicinal Chemistry, 1990 , vol. 33, # 7 p. 2015 - 2019
反应条件
1: 55 percent / butylamine / ethanol / 5 h / Heating 2: 52 percent / LiAlH4 / tetrahydrofuran / 4 h / Ambient temperature 3: 62 percent / K2CO3 / acetonitrile; toluene; H2O 4: 93 percent / NaBH3CN / acetonitrile; H2O / 0.25 h / Ambient temperature View Scheme
参考文献
Plenevaux; Dewey; Fowler; Guillaume; Wolf
Journal of Medicinal Chemistry, 1990 , vol. 33, # 7 p. 2015 - 2019
