17-Beta-雌二醇 3-甲醚合成路线 （共 45 条）
反应条件
methanol; sodium tetrahydroborate in dichloromethane T=50°C; 1 h;
参考文献
Saxena, Hari Om; Faridi, Uzma; Kumar; Luqman, Suaib; Darokar; Shanker, Karuna; Chanotiya, Chandan S.; Gupta; Negi, Arvind S.
Steroids, 2007 , vol. 72, # 13 p. 892 - 900
反应条件
potassium hydroxide in methanol; water T=65°C; 0.5 h;
参考文献
Pindur; Schall
Archiv der Pharmazie, 1994 , vol. 327, # 10 p. 637 - 642
反应条件
1: With ammonia; calcium; aniline in tetrahydrofuran T=-40 - -35°C; Birch Reduction; 2: With 4-methyl-pent-3-en-2-one in tetrahydrofuran
参考文献
US2008/300428 A1, ;
Page/Page column 2 ;
反应条件
potassium carbonate in acetonitrile 15 h; Heating;
参考文献
Muddana, Smita S.; Price, Aimee M.; MacBride, Megan M.; Peterson, Blake R.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 21 p. 4985 - 4988
反应条件
hydrogenchloride; ammonium chloride; ammonia; lithium; aniline in tetrahydrofuran; water
反应条件
neodymium(III) isopropoxide in isopropyl alcohol Heating;
参考文献
Organic and Biomolecular Chemistry, , vol. 3, # 3 p. 483 - 489
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; samarium diiodide in tetrahydrofuran T=22°C; 1.5 h;
参考文献
Kuenzer, H.; Stahnke, M.; Sauer, G.; Wiechert, R.
Tetrahedron Letters, 1991 , vol. 32, # 17 p. 1949 - 1952
反应条件
sulfuric acid; dihydrogen peroxide; iron(III) chloride in methanol T=35.5°C;
参考文献
Minailova, O. N.; Pivnitskii, K. K.
J. Gen. Chem. USSR (Engl. Transl.), 1981 , vol. 51, # 6 p. 1437 - 1438,1219 - 1220
反应条件
sulfuric acid; dihydrogen peroxide; iron(III) chloride in methanol T=35.5°C;
参考文献
Minailova, O. N.; Pivnitskii, K. K.
J. Gen. Chem. USSR (Engl. Transl.), 1981 , vol. 51, # 6 p. 1437 - 1438,1219 - 1220
反应条件
aluminium trichloride; sodium iodide in dichloromethane; acetonitrile 5.5 h; Ambient temperature;
参考文献
Node, Manabu; Ohta, Keiichiro; Kajimoto, Tetsuya; Nishide, Kiyoharu; Fujita, Eiichi; Fuji, Kaoru
Chemical & Pharmaceutical Bulletin, 1983 , vol. 31, # 11 p. 4178 - 4180
