2-(甲氧羰基)-3-甲基丁酸合成路线 （共 6 条）
反应条件
potassium hydroxide in methanol 1.) 1 h, r.t., 2.) 3 h, reflux;
参考文献
Nader, Franz W.; Brecht, Angelika; Kreisz, Siegfried
Chemische Berichte, 1986 , vol. 119, # 4 p. 1196 - 1207
反应条件
1: methyl acetate 2: aqueous ether; nitrogen oxides View Scheme
参考文献
Fischer,E.; Brauns
Chemische Berichte, 1914 , vol. 47, p. 3184
Chem. Zentralbl., 1914 , vol. 85, # II p. 981
反应条件
1: concentrated sulfuric acid / 100 °C 2: methyl acetate 3: aqueous ether; nitrogen oxides View Scheme
参考文献
Fischer,E.; Brauns
Chemische Berichte, 1914 , vol. 47, p. 3184
Chem. Zentralbl., 1914 , vol. 85, # II p. 981
反应条件
d-isopropylmalonic acid methyl ester-amide;
参考文献
Fischer,E.; Brauns
Chemische Berichte, 1914 , vol. 47, p. 3184
Chem. Zentralbl., 1914 , vol. 85, # II p. 981
Full Text Show Details
Fischer,E.; Brauns
Chem. Zentralbl., 1914 , vol. 85, # II p. 981
反应条件
4-methyl-morpholine in tetrahydrofuran
参考文献
Novartis Corporation
Patent: US5753652 A1, 1998 ;
反应条件
piperidine; pyridine Stetter reaction; Heating;
参考文献
Hayen; Koch; Saak; Haase; Metzger
Journal of the American Chemical Society, 2000 , vol. 122, # 50 p. 12458 - 12468
