1-(4-甲基苯甲酰基)-1H-咪唑合成路线 （共 13 条）
反应条件
in tetrahydrofuran T=20°C; Inert atmosphere;
参考文献
Jorgensen, Charlotte G.; Frolund, Bente; Kehler, Jan; Jensen, Anders A.
ChemMedChem, 2011 , vol. 6, # 4 p. 725 - 736
反应条件
triethylamine in dichloromethane T=20°C;
参考文献
Lee, Jung June; Kim, Jihye; Jun, Young Moo; Lee, Byung Min; Kim, Byeong Hyo
Tetrahedron, 2009 , vol. 65, # 43 p. 8821 - 8831
反应条件
pyridine 12 h; Ambient temperature;
参考文献
Saczewski, Franciszek
Heterocycles, 1994 , vol. 37, # 2 p. 689 - 692
反应条件
in acetonitrile 15 min, r.t; 40 min, 40 degC;
参考文献
Kitagawa, Tokujiro; Kuroda, Hiroko; Sasaki, Hideaki; Kawasaki, Koichi
Chemical & Pharmaceutical Bulletin, 1987 , vol. 35, # 10 p. 4294 - 4301
反应条件
hydroxylamine in water; acetonitrile T=23°C; 14 h;
参考文献
Yoganathan, Sabesan; Miller, Scott J.
Organic Letters, 2013 , vol. 15, # 3 p. 602 - 605
反应条件
1: hydroxylamine / acetonitrile; water / 14 h / 23 °C 2: 4-nitrophenylsulfonyl chloride; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 2 h / 0 °C / |Inert atmosphere View Scheme
参考文献
Yoganathan, Sabesan; Miller, Scott J.
Organic Letters, 2013 , vol. 15, # 3 p. 602 - 605
反应条件
in tetrahydrofuran Inert atmosphereReflux;
参考文献
Phan, Diem H. T.; Kim, Byoungmoo; Dong, Vy M.
Journal of the American Chemical Society, 2009 , vol. 131, # 43 p. 15608 - 15609
反应条件
ammonium acetate; triethylamine T=80°C; 3 h; Ionic liquid;
参考文献
Lee, Kwan Soo; Kim, Kee D.
Synthetic Communications, 2011 , vol. 41, # 23 p. 3497 - 3500
反应条件
1H-imidazole; potassium chloride in water; acetonitrile T=25 - 50°C; ΔH(excit.), ΔS(excit.), ΔG(excit.); KineticsThermodynamic data;
参考文献
Seoud, Omar A. El; Menegheli, Paulo; Pires, Paulo A. R.; Kiyan, Nilo Z.
Journal of Physical Organic Chemistry, 1994 , vol. 7, # 8 p. 431 - 436
反应条件
hydrogenchloride in N,N-dimethyl-formamide
4 h; Ambient temperature;
参考文献
Ohta, Shunsaku; Tsujimura, Atsuhiko; Okamoto, Masao
Chemical & Pharmaceutical Bulletin, 1981 , vol. 29, # 10 p. 2762 - 2768
