3-乙基-1-辛基-3-吡啶-4-基哌啶-2,6-二酮合成路线 (共 2 条)
反应条件
caesium carbonate in acetonitrile 0.5 h; Heating;
参考文献
Leung; Rowlands; Jarman; Foster; Griggs; Wilman
Journal of Medicinal Chemistry, 1987 , vol. 30, # 9 p. 1550 - 1554
反应条件
1: 61 percent / RhCl3*3H2O, Ph3P, anh. NaHCO3 / 20 h / Heating 2: Triton B / 2-methyl-propan-2-ol / 3 h 3: 4.17 g / conc. H2SO4 / acetic acid / 3 h / Heating 4: 90 percent / Cs2CO3 / acetonitrile / 0.5 h / Heating View Scheme
参考文献
Leung; Rowlands; Jarman; Foster; Griggs; Wilman
Journal of Medicinal Chemistry, 1987 , vol. 30, # 9 p. 1550 - 1554