1-(4-乙基-3-硝基苯基)乙酮合成路线 （共 2 条）
反应条件
sulfuric acid; nitric acid T=0 - 5°C; 0.25 h;
参考文献
AMGEN INC.; MEMORY PHARMACEUTICALS CORPORATION
Patent: WO2007/103260 A1, 2007 ;
Location in patent: Page/Page column 59-60 ;
WO 2007/103260 A1
反应条件
1: palladium / Hydrogenation
2: aqueous H2SO4; aqueous NaNO2 / Eintragen der Reaktionsloesung in siedende wss. H2SO4
3: K2S2O8; aqueous NaOH
View Scheme
参考文献
Kitahonoki
Chemical and Pharmaceutical Bulletin, 1959 , vol. 7, p. 114,117
