2'-脱氧胞苷-5'-单磷酸合成路线 (共 19 条)
反应条件
tris(p-nitrophenyl)phosphate T=50°C; Erwina herbicola 47/3 cells;
参考文献
Chemistry of Natural Compounds, , vol. 25, # 5 p. 626 - 627
Khimiya Prirodnykh Soedinenii, , vol. 25, # 5 p. 732 - 733
反应条件
ammonium hydroxide in water T=65°C; Hydrolysis; 6 h;
参考文献
Tetrahedron Letters, , vol. 41, # 37 p. 7173 - 7176
反应条件
phosphodiesterase I in various solvent(s) T=37°C; Hydrolysis; pH=7.6; 1 h; Enzymatic reaction; Product distribution; Further Variations:Reagentsother nucleotide, var. substrate concentrations;
参考文献
Journal of the American Chemical Society, , vol. 122, # 24 p. 5671 - 5677
反应条件
1: TPS-TAZ / pyridine / 2 h / 25 °C 2: NH4OH / H2O / 1 h / 25 °C 3: NH4OH / H2O / 6 h / 65 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 41, # 37 p. 7173 - 7176
反应条件
1: pyridine / und Erwaermen des Reaktionsprodukts mit wss.Essigsaeure 2: palladium; ethanol; water / Hydrogenation View Scheme
参考文献
Journal of the Chemical Society, , p. 34,37
反应条件
1: pyridine / und Erwaermen des Reaktionsprodukts mit 4-Methyl-morpholin in Benzol 2: palladium; ethanol; water / Hydrogenation View Scheme
参考文献
Journal of the Chemical Society, , p. 34,37
反应条件
1: acetic acid; water 2: pyridine / und Erwaermen des Reaktionsprodukts mit 4-Methyl-morpholin in Benzol 3: palladium; ethanol; water / Hydrogenation View Scheme
参考文献
Journal of the Chemical Society, , p. 34,37
反应条件
T=20°C; pH = 1; Rate constant;
参考文献
Journal of the American Chemical Society, , vol. 115, # 6 p. 2437 - 2440
反应条件
acetate buffer; bovine spleen phosphodiesterase II T=37°C; pH=6.0; 1 h; Enzyme kinetics;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 1 p. 289 - 291
反应条件
acetate buffer; bovine spleen phosphodiesterase II T=37°C; pH=6.0; 1 h; Enzyme kinetics;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 1 p. 289 - 291