[(2R,3R)-3-乙酰氧基-2-[(2,2-二氯乙酰基)氨基]-3-(4-硝基苯基)丙基]乙酸酯合成路线 (共 3 条)
反应条件
1: Novozym 435 / acetonitrile / 24 h / 20 °C / pH 7 / aq. phosphate buffer; Enzymatic reaction 2: Novozym 435 / acetonitrile / 3 h / 20 °C / Inert atmosphere; Enzymatic reaction View Scheme
参考文献
Bizerra, Ayla M.C.; Montenegro, Tasso G.C.; Lemos, Telma L.G.; De Oliveira, Maria C.F.; De Mattos, Marcos C.; Lavandera, Ivan; Gotor-Fernandez, Vicente; De Gonzalo, Gonzalo; Gotor, Vicente
Tetrahedron, 2011 , vol. 67, # 16 p. 2858 - 2862
反应条件
Novozym 435 in acetonitrile T=30°C; pH=7; 24 h; aq. phosphate bufferEnzymatic reaction; regioselective reaction;
参考文献
Bizerra, Ayla M.C.; Montenegro, Tasso G.C.; Lemos, Telma L.G.; De Oliveira, Maria C.F.; De Mattos, Marcos C.; Lavandera, Ivan; Gotor-Fernandez, Vicente; De Gonzalo, Gonzalo; Gotor, Vicente
Tetrahedron, 2011 , vol. 67, # 16 p. 2858 - 2862
反应条件
Novozym 435 in 1,4-dioxane T=20°C; pH=7; 24 h; aq. phosphate bufferEnzymatic reaction; regioselective reaction;
参考文献
Bizerra, Ayla M.C.; Montenegro, Tasso G.C.; Lemos, Telma L.G.; De Oliveira, Maria C.F.; De Mattos, Marcos C.; Lavandera, Ivan; Gotor-Fernandez, Vicente; De Gonzalo, Gonzalo; Gotor, Vicente
Tetrahedron, 2011 , vol. 67, # 16 p. 2858 - 2862