2',3',5'-三乙酰基-5-氮杂胞苷合成路线 （共 3 条）
反应条件
1: With tin(IV) chloride in dichloromethane T=0 - 5°C; 6 h; Inert atmosphere; 2: With water; sodium hydrogencarbonate in dichloromethane T=10°C; 0.5 h; Product distribution / selectivity;
参考文献
PHARMION LLC; RAJENDIRAN, Chinnapillai; NAGARAJAN, Periyandi; VENKATESWARLAU, Jasti
Patent: WO2012/135405 A1, 2012 ;
Location in patent: Page/Page column 64-67 ;
反应条件
trifluorormethanesulfonic acid in acetonitrile T=20 - 25°C; Product distribution / selectivity;
参考文献
SICOR INC.; BIGATTI, Ettore; LUX, Giovanna; PAIOCCHI, Maurizio; GIOLITO, Andrea; TOSI, Simone
Patent: WO2010/17374 A1, 2010 ;
Location in patent: Page/Page column 17-18 ;
反应条件
methanol; sodium methylate T=20 - 25°C; 1.58333 h; Product distribution / selectivity;
参考文献
SICOR INC.; BIGATTI, Ettore; LUX, Giovanna; PAIOCCHI, Maurizio; GIOLITO, Andrea; TOSI, Simone
Patent: WO2010/17374 A1, 2010 ;
Location in patent: Page/Page column 18 ;
