1: 1.) 1 M BH3, 2.) HCl (gas) / 1.) THF, 22 deg C, 22 h, 2.) MeOH, 0 deg C 2: 75 percent / NaOH / 2-methoxy-ethanol; H2O / 1.) 22 deg C, 6 h, 2.) 5 deg C, 15 h 3: 1.) triethylamine, isobutyl chloroformate, 2.) triethylamine / 1.) DMF, 30 min, 2.) DMF, 20 h 4: 68 percent / 1.0 N NaOH / 2-methoxy-ethanol / 3 h / 22 °C View Scheme