Zn(ClO4)2*6H2O in diethyl ether T=23°C; 16 h;

1: 4-Bromo-2-chlorophenol With sodium hydride in tetrahydrofuran T=0 - 20°C; 1 h; 2: acetyl chloride in tetrahydrofuran T=20°C; 5 h; Further stages.;

1: 2-chlorophenol; phenol With vanadate(V)-dependent bromoperoxidase I from Ascophyllum nodosum; dihydrogen peroxide; sodium bromide in water; tert-butyl alcohol T=25°C; 24 h; Enzymatic reaction; 2: acetic anhydride With Zn(ClO4)2*6H2O in diethyl ether T=23°C; 16 h; ConcentrationReagent/catalyst;

1: dihydrogen peroxide; vanadate(V)-dependent bromoperoxidase I from Ascophyllum nodosum; sodium bromide / tert-butyl alcohol; water / 72 h / 23 °C / pH 6.2 / |Enzymatic reaction 2: Zn(ClO4)2*6H2O / diethyl ether / 16 h / 23 °C View Scheme