[(3-甲基丁-2-烯-1-基)硫代]苯合成路线 （共 66 条）
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
McCullough, Dennis W.; Bhupathy; Piccolino, Elvio; Cohen, Theodore
Tetrahedron, 1991 , vol. 47, # 47 p. 9727 - 9736
反应条件
phosphoric acid; phosphorus pentoxide in benzene
20 h; Heating;
参考文献
Waugh, Kristy M.; Berlin, K. Darrell; Ford, Warren T.; Holt, Elizabeth M.; Carrol, John P.; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 1 p. 116 - 124
反应条件
1: hydrogen / <Ru3O(CH3COO)6(H2O)3>(1+)*CH3COO(1-) / dimethylformamide / 2 h / 80 °C / 3040 Torr / other catalyst: RuO2*nH2O
2: Na, ethanol / Ambient temperature
3: 40 percent / hydrogen / RuO2*nH2O / methanol / 48 h / 60 °C / 6080 Torr
View Scheme
参考文献
Cere, Vanda; Massaccesi, Franco; Pollicino, Salvatore; Ricci, Alfredo
Synthetic Communications, 1996 , vol. 26, # 5 p. 899 - 907
反应条件
1.1: n-BuLi / tetrahydrofuran; hexane / 1 h / -78 - 0 °C
1.2: 77 percent / TMEDA / tetrahydrofuran; hexane / 3 h / -78 - 20 °C
2.1: lithium 4,4'-di-tert-butylbiphenyl / tetrahydrofuran / -11 °C
2.2: 21 percent / tetrahydrofuran / -11 °C
View Scheme
参考文献
Streiff, Stephane; Ribeiro, Nigel; Desaubry, Laurent
Journal of Organic Chemistry, 2004 , vol. 69, # 22 p. 7592 - 7598
反应条件
1: 75.8 percent / 85percent H3PO4, P2O5 / benzene / 20 h / Heating
2: 60.3 percent / SnCl4 / benzene / 5 h / Ambient temperature
3: 94 percent / LiAlH4 / diethyl ether / 24 h / Heating
4: 73.1 percent / methanol / 26 h / Ambient temperature
5: 1.) n-BuLi / 1.) ether, hexane, 5 min, 2.) ether, hexane, RT, 36 h
View Scheme
参考文献
Dawson, Marcia I.; Hobbs, Peter D.; Derdzinski, Krzysztof; Chan, Rebecca L.-S.; Gruber, John; et al.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1516 - 1531
反应条件
in tetrahydrofuran; diethyl ether
T=0°C; 0.5 h;
参考文献
Fugami, Keigo; Oshima, Koichiro; Utimoto, Kiitiro; Nozaki, Hitosi
Tetrahedron Letters, 1986 , vol. 27, # 19 p. 2161 - 2164
