1-环戊烯-1-甲酸乙酯合成路线 （共 23 条）
反应条件
potassium hydroxide in methanol 2 h; Heating;
参考文献
Palaty; Abbott
Journal of Medicinal Chemistry, 1995 , vol. 38, # 17 p. 3398 - 3406
反应条件
tris-(2-chloro-ethyl)-amine; triphenylphosphine; diethylazodicarboxylate in ethanol; benzene
T=10 - 20°C; Substitution; elimination; 8 h;
参考文献
Appella, Daniel H.; Christianson, Laurie A.; Klein, Daniel A.; Richards, Michele R.; Powell, Douglas R.; Gellman, Samuel H.
Journal of the American Chemical Society, 1999 , vol. 121, # 33 p. 7574 - 7581
反应条件
1: 1.) sodium borohydride, 2.) 6 M aq. HCl / methanol / 1 h / 0 °C
2: Et3N / CH2Cl2 / 1 h / Ambient temperature
3: DBU / tetrahydrofuran / 24 h / Ambient temperature
View Scheme
参考文献
Palaty; Abbott
Journal of Medicinal Chemistry, 1995 , vol. 38, # 17 p. 3398 - 3406
反应条件
pyridine; p-toluenesulfonyl chloride
参考文献
Kronenthal; Becker
Journal of the American Chemical Society, 1957 , vol. 79, p. 1095,1101
反应条件
samarium diiodide; methyl chloroformate in tetrahydrofuran
Ambient temperature;
参考文献
Lu, Ling; Fang, Jim-Min; Lee, Gene-Hsiang; Wang, Yu
Journal of the Chinese Chemical Society, 1997 , vol. 44, # 3 p. 279 - 289
反应条件
triethylamine in chloroform
1 h; Heating; Yield given;
参考文献
Beagley, Brian; Larsen, David S.; Pritchard, Robin G.; Stoodley, Richard J.; Whiting, Andrew
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 1127 - 1137
反应条件
samarium diiodide in tetrahydrofuran
Ambient temperature;
参考文献
Lu, Ling; Fang, Jim-Min; Lee, Gene-Hsiang; Wang, Yu
Journal of the Chinese Chemical Society, 1997 , vol. 44, # 3 p. 279 - 289
反应条件
dihydrogen peroxide; acetic acid in tetrahydrofuran
T=-45 - -10°C; 0.5 h;
参考文献
Ko, Yen-Chun; Zhu, Jia-Liang
Synthesis, 2007 , # 23 p. 3659 - 3665
反应条件
phosphorus pentachloride
参考文献
Cook; Linstead
Journal of the Chemical Society, 1934 , p. 946,954
反应条件
potassium iodide in acetone
Heating;
参考文献
Nielsen, Jens Kaergaard; Madsen, Joergen Oegaard
Tetrahedron: Asymmetry, 1994 , vol. 5, # 3 p. 403 - 410
