5-硝基苯并呋喃-2-甲酸合成路线 (共 27 条)
反应条件
water; sodium hydroxide in methanol 0.5 h; Heating;
参考文献
Aboraia, Ahmed S.; Yee, Sook Wah; Gomaa, Mohamed Sayed; Shah, Nikhil; Robotham, Anna C.; Makowski, Bart; Prosser, David; Brancale, Andrea; Jones, Glenville; Simons, Claire
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 14 p. 4939 - 4946
反应条件
1: With acetic anhydride T=35°C; 0.25 h; 2: With sodium acetate T=125°C; 8 h;
参考文献
WO2013/175499 A2, ;
Page/Page column 21-22 ;
反应条件
nitric acid; tin(IV) chloride in dichloromethane T=0°C; 2 h;
参考文献
Canadian Journal of Chemistry, , vol. 61, p. 2287 - 2290
反应条件
sodium acetate; acetic anhydride T=110°C; 3 h;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 56, # 9 p. 2762 - 2767
反应条件
nitric acid; tin(IV) chloride in dichloromethane T=0°C; 2 h;
参考文献
Canadian Journal of Chemistry, , vol. 61, p. 2287 - 2290
反应条件
potassium hydroxide in 1,4-dioxane 1 h; Heating;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 58, # 10 p. 2821 - 2825
反应条件
1.1: sodium hydroxide / water / 3 h / 30 - 100 °C 2.1: sulfuric acid; nitric acid / 5 - 35 °C 3.1: acetic anhydride / 0.25 h / 35 °C 3.2: 8 h / 125 °C View Scheme
反应条件
1: potassium carbonate; butanone 2: ethanolic KOH-solution View Scheme
参考文献
Nippon Kagaku Zasshi, , vol. 73, p. 282,285
Chem.Abstr., , p. 9957
Gazzetta Chimica Italiana, , vol. 86, p. 1257,1267
反应条件
potassium hydroxide; ethanol
参考文献
Journal of the Chemical Society, , vol. 123, p. 3381
参考文献
Nippon Kagaku Zasshi, , vol. 73, p. 282,285
Chem.Abstr., , p. 9957
Gazzetta Chimica Italiana, , vol. 86, p. 1257,1267