1H-吲哚-2-基(苯基)甲酮合成路线 （共 61 条）
反应条件
1: 65 percent / NaOH; K2CO3
2: aq. NH4Cl; indium powder / methanol / 4.5 h / Heating
View Scheme
参考文献
Han, Rongbi; Chen, Shen; Lee, Sun Jung; Qi, Fang; Wu, Xue; Kim, Byeong Hyo
Heterocycles, 2006 , vol. 68, # 8 p. 1675 - 1684
反应条件
1: 65 percent / NaOH; K2CO3
2: aq. NH4Cl; indium powder / methanol / 4.5 h / Heating
View Scheme
参考文献
Han, Rongbi; Chen, Shen; Lee, Sun Jung; Qi, Fang; Wu, Xue; Kim, Byeong Hyo
Heterocycles, 2006 , vol. 68, # 8 p. 1675 - 1684
反应条件
1: 60 percent / 1.) 4N KOH, 2.) 10percent HCl / H2O; methanol / 2 h / 70 °C
2: 82 percent / iPr2EtN / CH2Cl2 / 1 h / 0 °C
3: 80 percent / tetra-n-butylammonium bisulfate, 50percent KOH / CH2Cl2; H2O / 2 h / -20 °C
4: 100 percent / 10percent HCl / tetrahydrofuran / 2 h / Heating
5: 77 percent / trifluoroacetic anhydride / CH2Cl2 / 2 h / Heating
6: 52 percent / tetrahydrofuran / 1 h / -78 °C
7: 70 percent / 4N KOH / methanol / 5 h / Heating
View Scheme
参考文献
Miki, Yasuyoshi
Heterocycles, 1997 , vol. 45, # 6 p. 1143 - 1150
反应条件
1: 82 percent / iPr2EtN / CH2Cl2 / 1 h / 0 °C
2: 80 percent / tetra-n-butylammonium bisulfate, 50percent KOH / CH2Cl2; H2O / 2 h / -20 °C
3: 100 percent / 10percent HCl / tetrahydrofuran / 2 h / Heating
4: 77 percent / trifluoroacetic anhydride / CH2Cl2 / 2 h / Heating
5: 52 percent / tetrahydrofuran / 1 h / -78 °C
6: 70 percent / 4N KOH / methanol / 5 h / Heating
View Scheme
参考文献
Miki, Yasuyoshi
Heterocycles, 1997 , vol. 45, # 6 p. 1143 - 1150
反应条件
1: 52 percent / tetrahydrofuran / 1 h / -78 °C
2: 70 percent / 4N KOH / methanol / 5 h / Heating
View Scheme
参考文献
Miki, Yasuyoshi
Heterocycles, 1997 , vol. 45, # 6 p. 1143 - 1150
反应条件
1: 77 percent / trifluoroacetic anhydride / CH2Cl2 / 2 h / Heating
2: 52 percent / tetrahydrofuran / 1 h / -78 °C
3: 70 percent / 4N KOH / methanol / 5 h / Heating
View Scheme
参考文献
Miki, Yasuyoshi
Heterocycles, 1997 , vol. 45, # 6 p. 1143 - 1150
反应条件
1: 80 percent / tetra-n-butylammonium bisulfate, 50percent KOH / CH2Cl2; H2O / 2 h / -20 °C
2: 100 percent / 10percent HCl / tetrahydrofuran / 2 h / Heating
3: 77 percent / trifluoroacetic anhydride / CH2Cl2 / 2 h / Heating
4: 52 percent / tetrahydrofuran / 1 h / -78 °C
5: 70 percent / 4N KOH / methanol / 5 h / Heating
View Scheme
参考文献
Miki, Yasuyoshi
Heterocycles, 1997 , vol. 45, # 6 p. 1143 - 1150
反应条件
1: 100 percent / 10percent HCl / tetrahydrofuran / 2 h / Heating
2: 77 percent / trifluoroacetic anhydride / CH2Cl2 / 2 h / Heating
3: 52 percent / tetrahydrofuran / 1 h / -78 °C
4: 70 percent / 4N KOH / methanol / 5 h / Heating
View Scheme
参考文献
Miki, Yasuyoshi
Heterocycles, 1997 , vol. 45, # 6 p. 1143 - 1150
反应条件
1: 95 percent / benzene / 12 h / Heating
2: 73 percent / LDA / tetrahydrofuran; cyclohexane / 1.) -80 deg C, 30 min, 2.) RT, overnight
View Scheme
参考文献
Takeda, Yohko; Kikuchi, Akiko; Terashima, Masanao
Heterocycles, 1993 , vol. 35, # 2 p. 573 - 576
反应条件
1: 60 percent / KOH / ethanol / 3 h / 20 °C
2: 57 percent / methanol / 1.5 h / Irradiation
View Scheme
参考文献
Kar, Samiran; Lahiri, Saswati
Journal of the Indian Chemical Society, 1999 , vol. 76, # 11-12 p. 607 - 610
