1H-吲哚-2-基(苯基)甲酮合成路线 (共 61 条)
反应条件
sodium hydride 1.) DMSO, 1 h;
参考文献
Rekhter
Chemistry of Heterocyclic Compounds, 1996 , vol. 32, # 4 p. 408 - 417
反应条件
1,10-phenanthroline; carbon monoxide; palladium diacetate in N,N-dimethyl-formamide
T=80°C; P=775.722 Torr; 16 h;
参考文献
Davies, Ian W.; Smitrovich, Jacqueline H.; Sidler, Rick; Qu, Chuanxing; Gresham, Venita; Bazaral, Charles
Tetrahedron, 2005 , vol. 61, # 26 p. 6425 - 6437
反应条件
bis-triphenylphosphine-palladium(II) chloride; carbon monoxide; tin(ll) chloride in 1,4-dioxane
T=100°C; P=15200 Torr;
参考文献
Scott, Tricia L.; Soederberg, Bjoern C. G.
Tetrahedron, 2003 , vol. 59, # 33 p. 6323 - 6332
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in 1,4-dioxane
T=85°C; P=9000.9 Torr; 60 h; Inert atmosphereAutoclave;
参考文献
Arthuls, Martin; Pontikis, Renee; Florent, Jean-Claude
Organic Letters, 2009 , vol. 11, # 20 p. 4608 - 4611
反应条件
carbon monoxide; [Rh(CO)2(Me2NCH2CH2NMe2)][RhCl2(CO)2] in tetrahydrofuran
T=100°C; P=5171.62 Torr; 20 h; Autoclave;
参考文献
Okuro, Kazumi; Gurnham, Joanna; Alper, Howard
Journal of Organic Chemistry, 2011 , vol. 76, # 11 p. 4715 - 4720
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in toluene
T=90°C; P=760.051 Torr; 2 h; Inert atmosphereAutoclave;
参考文献
Arthuls, Martin; Pontikis, Renee; Florent, Jean-Claude
Organic Letters, 2009 , vol. 11, # 20 p. 4608 - 4611
反应条件
10percent NaOH in ethanol
12 h; Heating;
参考文献
Mahboobi, Siavosh; Teller, Steffen; Pongratz, Herwig; Hufsky, Harald; Sellmer, Andreas; Botzki, Alexander; Uecker, Andrea; Beckers, Thomas; Baasner, Silke; Schaechtele, Christoph; Ueberall, Florian; Kassack, Matthias U.; Dove, Stefan; Boehmer, Frank-D.
Journal of Medicinal Chemistry, 2002 , vol. 45, # 5 p. 1002 - 1018
反应条件
iodine; potassium carbonate in methanol
T=60°C; 2 h;
参考文献
Gao, Wen-Chao; Jiang, Shan; Wang, Ruo-Lin; Zhang, Chi
Chemical Communications, 2013 , vol. 49, # 43 p. 4890 - 4892
反应条件
1: 2-phenyl-2-oxoethyldimethylsulfonium bromide With caesium carbonate in anhydrous xylene
T=20°C;
2: N-(2-(chloromethyl)phenyl)-4-methylbenzenesulfonamide in anhydrous xylene
T=20°C;
参考文献
Yang, Qing-Qing; Xiao, Cong; Lu, Liang-Qiu; An, Jing; Tan, Fen; Li, Bin-Jie; Xiao, Wen-Jing
Angewandte Chemie - International Edition, 2012 , vol. 51, # 36 p. 9137 - 9140
反应条件
sodium ethanolate in dimethyl sulfoxide
T=100°C; 24 h; Inert atmosphere;
参考文献
Pan, Changduo; Jin, Hongming; Liu, Xu; Cheng, Yixiang; Zhu, Chengjian
Chemical Communications, 2013 , vol. 49, # 28 p. 2933 - 2935