2-甲氨基-5-氯二苯甲酮合成路线 （共 61 条）
反应条件
hydrogenchloride in methanol; water T=80°C; pH=2 - 5;
参考文献
Journal of Physical Organic Chemistry, , vol. 18, # 2 p. 156 - 161
反应条件
potassium hydroxide in methanol 3.75 h; Heating;
参考文献
Journal of Organic Chemistry, , vol. 45, # 9 p. 1675 - 1681
反应条件
1.1: NaOMe / methanol / 5 °C 2.1: LDA / tetrahydrofuran; hexane / 0.5 h / -78 °C 2.2: -78 °C 3.1: cc. HCl; H2O / methanol / 18 h / Heating View Scheme
参考文献
Helvetica Chimica Acta, , vol. 83, # 3 p. 603 - 615
反应条件
in chloroform 8 h; Ambient temperature;
参考文献
Konwar, D.; Boruah, R. C.; Sandhu, J. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 10 p. 975 - 976
反应条件
hydrogenchloride T=25°C; also in micellar system; Rate constant;
参考文献
Journal of Pharmaceutical Sciences, , vol. 80, # 5 p. 459 - 468
反应条件
potassium hydroxide in ethanol Heating;
参考文献
Pharmazie, , vol. 45, # 12 p. 933 - 934
反应条件
hydrogenchloride; water in methanol Hydrolysis; 18 h; Heating;
参考文献
Helvetica Chimica Acta, , vol. 83, # 3 p. 603 - 615
反应条件
1: 100 percent / NaOH; K2CO3; tetrabutylammonium hydrosulfate / toluene / 2 h / 18 - 20 °C 2: 98 percent / aq. H2SO4 / ethanol / Heating View Scheme
参考文献
Russian Journal of General Chemistry, , vol. 74, # 9 p. 1467 - 1468
反应条件
1: KOH / ethanol / Heating 2: KOH / ethanol / Heating View Scheme
参考文献
Pharmazie, , vol. 45, # 12 p. 933 - 934
反应条件
hydrogenchloride T=75°C; rate constants; also in the presence of 0.1 M NaOH or pH3 buffer;
参考文献
Journal of Pharmacy and Pharmacology, , vol. 46, # 2 p. 1065
